Drugs of a pharmacological group of corticosteroids are applied only in the most extreme cases – shock, brain tumors, blood diseases, severe toxic-allergic and infectious diseases. These are very strong drugs, so they have a large number of side effects. However, the use of corticosteroids has brought back to life and saved many people. One of the representatives of this group of medication is Decadron. The instruction for use describes this medicine as a potent glucocorticosteroid medication of synthetic origin, optionally containing fluorine (derived torpedinidae). Decadron has a pronounced antitoxic, antishock, anti-allergic and anti-inflammatory effect.
The spectrum of action
This drug belongs to the synthetic analogues of glucocorticosteroid hormones (GCS), which produces adrenal cortex. The body synthesizes about 30 hormones-corticosteroids. They have diverse effects on the human body, including increase of its resistance to various negative factors, reduce sensitivity to pain. Decadron rapidly reduces inflammation, itching, pain, swelling, symptoms of allergic reactions. The drug stimulates the release of blood of the neurotransmitter adrenaline, which contributes to the withdrawal of a man from a state of severe shock.
Like most corticosteroids, Decadron has a dual pharmacological action. This medication suppresses the immune system and the ability of body cells to multiply (proliferation). On the one hand, it’s bad. However, in the treatment of autoimmune and oncological diseases, this property of the drug is, on the contrary, demanded. Also this remedy has a negative effect on the growth of connective tissues. Its useful for the prevention of the formation of adhesions but it is harmful for scarring of the myocardium (heart muscle) after a heart attack. Therefore, it is strictly prohibited to take Decadron by your own. The medicine is available in the form, of tablets, solution for intramuscular and intravenous injections, and eye drops.
Indications for use
The scope of the fast-acting drug Decadron is quite large. Firstly, the medication is used for toxic, surgical, traumatic or burn shock. This glucocorticosteroid is prescribed for traumatic brain injuries accompanied by bleeding in the brain, meningitis, encephalitis, neurosurgical operations. The drug helps to cope with endocrine diseases, subacute thyroiditis, congenital hyperplasia, primary and secondary adrenal insufficiency. Decadron is used in the connective tissue diseases, acute dermatoses, granuloma annulare, lupus erythematosus, rheumatism, severe allergic reaction (eg, severe asthma), anaphylactic shock. The drug facilitates the condition of patients with serious diseases of the blood thrombocytopenic purple, agranulocytosis, leukemia, hemolytic anemia. In ophthalmic practice the drug is claimed in the treatment of episcleritis, blepharitis, iridocyclitis, allergic conjunctivitis and also after operations on the organs of vision.
According to the instructions, the pills of Decadron are taken at short courses for inflammation and relief of allergic reactions. Daily dose in the acute period of the disease is from 10 to 15 milligrams, as maintenance therapy: from 2 to 4.5 milligrams. For injections they use from 4 to 20 milligrams of the medication. The solution for eye is instilled every 2 hours into the conjunctival SAC 1 – 2 drops.
Drug contraindications and side effects
Except for individual intolerance of the drug, contraindications to the use of Decadron include kidney and liver failure, cardiovascular disease, immunodeficiency, diverticulitis, reflux esophagitis, peptic ulcer, poliomyelitis, diabetes mellitus, acute psychosis. The use of this medicine by pregnant women and children is possible only in case of health reasons.