Fasigyn is a medicinal product used in surgery and for the treatment of infectious diseases. We suggest you to find out the most useful information about the preparation, how to use it correctly and what precautions to take when applying the drug. So, about everything in order.
Fasigyn contains in its composition an active substance – tinidazole. So one tablet of the drug contains 500 mg of the active ingredient tinidazole. The composition of the drug includes a number of auxiliary substances, such as: corn starch, alginine acid, magnesium stearate, hypromellose, titanium dioxide and others.
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Indications for use of Fasigyn.
The main indications for the use of Fasigyn are various kinds of anaerobic infections. Such infections include:
Postoperative wound infections
Acute ulcerative gingivitis
Infectious diseases of soft tissues and skin
Postoperative prophylaxis of the gastrointestinal tract and gynecological diseases.
Form of issue
The form of release of the drug is a film-coated tablet. One tablet contains 500 mg of active ingredient tinidazole. One package contains one blister and four tablets.
The drug is issued by prescription. For the safety of the drug it is very important to comply with all rules and conditions for storage of the drug.
Pharmacodynamics of Fasigyn.
Pharmacodynamics of Fasigyn shows the properties of the drug, which are part of the substance. The drug is active against obligate and protozoa anaerobic bacteria. The drug works effectively against: Trichomonas vaginalis, Giardia lamblia and Entamoeba histolytica. The main method of the drug is penetration into cells affected by microorganisms and damage to DNA strands or inhibition of their synthesis.
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Fasigyn is active against such anaerobic bacteria:
Pharmacokinetics of Fasigyn.
Fasigyn allows to learn about the process of metabolism, absorption and excretion of the drug. After taking the drug, the active substances are rapidly absorbed. Complete dissolution of the drug in the body occurs two hours after ingestion. About 12% of the substance binds to proteins, the rest of the drug is excreted by the kidneys and liver.
If the drug is prescribed to women who are breastfeeding, then it is worth noting lactation. Because the drug is excreted through breast milk and can enter the baby’s body. If the drug is prescribed for people with kidney failure, then the drug does not change its pharmacokinetic properties.
Use of Fasigyn during pregnancy.
Use of Fasigyn during pregnancy is not recommended. But in the study of the drug, there were no abnormalities that would adversely affect the pregnant woman’s body and the development of the future baby’s body. Fasigyn during pregnancy can be used only when absolutely necessary, when the benefit to the mother is more important than the potential risk to the fetus.
When taking the drug during lactation it is necessary to refuse breastfeeding. Because the remnants of the drug are excreted from the body with the help of milk. Many doctors recommend to take out the first portion of milk, as in it that a high percentage of the drug is concentrated. It is also worth not to work with mechanical devices and driving a car.
Contraindications of Fasigyn.
The main contraindications for the use of Fasigyn are individual intolerance to the components of the drug. During treatment, you must refrain from drinking alcohol. Women who are in the process of lactation, should stop breastfeeding and start it five days after the end of taking the drug.
If during the administration of the drug in patients there is a neurological symptomatology, then the drug should be discarded. In the course of treatment, which exceeds seven days, it is necessary to monitor laboratory and clinical parameters.
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Side effects of Fasigyn.
All side effects of Fasigyn are based on the reactions of the body to the active substance in the drug. Let’s consider the main side effects of the drug Fasigyn.