Isoptin

Therapy and prevention of ischemic heart disease (chronic stable angina, vasospastic angina, unstable angina). Therapy and prevention of cardiac arrhythmias: supraventricular premature beats, chronic form of shimmer and artrial flutter (tachyarrhythmia), supraventricular paroxysmal tachycardia, hypertrophic cardiomyopathy, hypertensive crisis, hypertension.


Category:

Description

Indications for use

Therapy and prevention of ischemic heart disease (chronic stable angina, vasospastic angina, unstable angina). Therapy and prevention of cardiac arrhythmias: supraventricular premature beats, chronic form of shimmer and artrial flutter (tachyarrhythmia), supraventricular paroxysmal tachycardia, hypertrophic cardiomyopathy, hypertensive crisis, hypertension. You may buy isoptin on our website.

Drug Contraindications

Contraindications to the use of Isoptin are: heart failure, bradycardia, cardiogenic shock, sinoatrial block, and marked functional impairment of the contractility of the left ventricle, weak sinus node syndrome, severe arterial hypotension ( blood pressure is less than 90 mm of mercury collumn), atrio-ventricular blockade of the 2nd and 3rd degree (except for patients with pacemaker), a joint reception with colchicine, sertindole, aliskiren, dantrolene, increased sensitivity to verapamil and other auxiliary components of the drug, atrial fibrillation and atrial flutter in combination with Lown–Ganong–Levine syndrome or WPW syndrome (except for patients with pacemaker), the period of carrying a child and breastfeeding.

Method of application and dosage

The Solution is intended solely for intravenous administration. The injections should be done slowly for at least 2 minutes under continuous control of blood pressure and ECG. Elderly people perform the injection for 3 minutes (to reduce risk of adverse reactions). The optimal initial dose of Isoptin is 5-10 mg (0,075-0,15 mg/kg of body weight). If you notice an inadequate response of the body to the first introduction, then the re-appointed dose should be 10 mg (0.15 mg/kg of body weight). It should be entered in 30 minutes after the first injection. The tablets are intended for oral administration. The drug should be swallowed as a whole without resorption and chewing, and it should be washed by water. The reception of Isoptin is desirable during meal or immediately after meal. Isoptin can be bought on our website. The initial dose of the drug is usually 40-80 mg (frequency of reception is 3-4 times a day). The optimal dose of the drug must be appointed by a physician individually for each patient. Specialists take into account the severity and clinical picture of pathology. The average dose for all indications ranges from 240 to 480 mg per day. The daily dose of 480 mg should be increased in case of prolonged therapy. The maximum dose of Isoptin is required only in a hospital. The total duration of treatment is determined by a doctor. The treatment of functional disturbance of the liver should start with taking 1 tablet (40 mg) 2-3 times a day. Further dose is chosen individually.

Side effects

The use of Isoptin may cause following adverse reactions:

Central and peripheral nervous system: fatigue, dizziness, stiffness of the limbs, headache, depression, syncope, anxiety, asthenia, confusion, extrapyramidal disorders (shuffling gait, ataxia, difficulty swallowing, mask-like face, tremors of fingers and hands), drowsiness.

Cardiovascular system: tachycardia, bradycardia (less 50 beats/min), the worsening or development of heart failure, marked reduction in blood pressure; rarely, arrhythmias (including atrial and ventricular flicker), angina, until the occurrence of myocardial infarction (especially in patients with severe obstructive coronary disease); rapid intravenous – collapse, asystole, atrio-ventricular blockade of the 3rd  degree.

Digestive system: nausea, increased activity of alkaline phosphatase and hepatic transaminases, constipation (rare – diarrhea), increased appetite, gingival hyperplasia (swelling, pain, bleeding). Allergic reactions: hyperemia skin, skin itch, multiform exudative erythema (including Stevens-Johnson syndrome), skin rashes. Other side effects: very rarely – increased body mass, galactorrhea, agranulocytosis, arthritis, hyperprolactinemia, gynecomastia, pulmonary edema, transient loss of vision due to maximum plasma concentration (when it is administered intravenously), peripheral edema, asymptomatic thrombocytopenia.

Special instructions

Isoptin should be used with extreme caution in case of atrio-ventricular blockade of the 1st degree, chronic heart failure, bradycardia, renal and/or hepatic insufficiency, severe stenosis of the mouth of the aorta, obstructive hypertrophic cardiomyopathy, moderate or slight arterial hypotension, elderly patients, adolescents under 18 years and children (safety and efficacy of the drug has not been investigated), and myocardial infarction in the acute stage. If necessary, you can share the treatment of hypertension, angina beta-blockers and verapamil. However, you should avoid intravenous administration of beta-blockers in the background of the use of verapamil. The reception of verapamil can lead to the risk of adverse individual reactions (dizziness, drowsiness) that affects the ability of the patient to perform work associated with high speed of psychomotor reactions and concentration of attention.

Reviews

There are no reviews yet.

Be the first to review “Isoptin”

Related products

error: Content is protected !!