Rosuvastatin

The drug Rosuvastatin refers to the pharmacological group of hypolipidemic drugs. It lowers the level of cholesterol in the blood and is used to treat hypercholesterolemia, as well as for the prevention of atherosclerosis.


Description

The drug Rosuvastatin refers to the pharmacological group of hypolipidemic drugs. It lowers the level of cholesterol in the blood and is used to treat hypercholesterolemia, as well as for the prevention of atherosclerosis.
You can buy Rosuvastatin on our website.

Composition and form of release.

The drug Rosuvastatin is manufactured in the form of a tablet coated with a film coat for oral (ingestion). They have a light pink or pink color, a round shape and a biconvex surface. The main active ingredient of the drug is Rosuvastatin, its content in 1 tablet is 5, 10 and 20 mg. It also includes auxiliary substances, which include:
Starch.
Hypromellose.
The dye carmine.
Titanium dioxide.
Microcrystalline cellulose.
Triacetin.
Colloidal silicon dioxide.
Magnesium stearate.

Rosuvastatin tablets are packaged in a planar cell pack of 10 pieces. Cardboard pack contains 3 or 6 contour squares and instructions for use.

Pharmacodynamics and pharmacokinetics

The active component of tablets Rosuvastatin refers to lipid-lowering drugs. It suppresses (inhibits) the activity of the enzyme HMG-CoA reductase, which is responsible for the synthesis of the mevalonate cholesterol precursor. The drug directly affects liver cells (hepatocytes), which are responsible for the synthesis of endogenous (own) cholesterol in the body.
After taking the Rosuvastatin pill inside the active ingredient quickly, but not completely absorbed into the systemic bloodstream and evenly distributed in the tissues. It is practically not metabolized and is excreted unchanged mainly with feces.
By purchasing Rosuvastatin on our website you will receive a certified product.

Indications for use.

For taking Rosuvastatin tablets, several medical indications are distinguished, which include:
Primary hypercholesterolemia is a condition accompanied by an increase in the level of cholesterol in the blood.
Hypertriglyceridemia is an increased concentration of free fats (triglycerides) in the blood.
Family (hereditary) homozygous hypercholesterolemia.
Prevention of complications of atherosclerosis (deposition of cholesterol in the walls of arterial vessels with narrowing of their lumen), in particular angina pectoris, myocardial infarction, hypertensive disease, cerebral stroke in persons over the age of 50 years.
Also, the drug is used to slow the development of atherosclerosis as an adjunct to dietary recommendations.

Contraindications.

There are number of pathological and physiological conditions of the body, which are contraindications to the reception of tablets Rosuvastatin, they include:
Individual intolerance to any of the components of the drug.
Children under 18 years.

Pregnancy, lactation (breastfeeding), as well as the lack of adequate contraception in women of childbearing age, which makes it impossible to exclude pregnancy while using the drug.
Acute hepatic pathology, accompanied by a violation of its functional state and damage to hepatocytes with an increase in the level of enzymes hepatic transaminases in the blood.
Concomitant administration of the drug is cyclosporin.

Myopathy (pathology of striated skeletal musculature) or a predisposition to its development.
Use of the drug in a dosage of 40 mg is further contraindicated for persons with a predisposition to myopathy, chronic alcoholism, conditions leading to increased levels of Rosuvastatin in blood, renal insufficiency functional activity, development of myotoxity in patients receiving other medications containing enzyme inhibitors of HMG-CoA reductase , simultaneous reception of fibrates. Also, this dosage is not used in patients of Mongoloid race. These factors are the basis for the careful use of the drug with a lower dosage. Before the appointment of Rosuvastatin tablets, the doctor is convinced of the absence of contraindications.

Method of application and dosage.

On our site you can buy Rosuvastatin in unlimited quantities.
Rosuvastatin tablets are taken inside whole regardless of food. They are not chewed and washed down with a sufficient volume of water. Starting dosage is 5-10 mg per day (single dose tablets). If necessary, increase it to 20 mg per day. The daily dose should not exceed 40 mg. The need to use a dose of 40 mg is determined by severe hypercholesterolemia, but significantly increases the risk of side effects. Patients with concomitant functional hepatic failure, kidney disease, a predisposition to myopathy and representatives of Mongoloid race are recommended to use therapeutic dose 5 mg. Duration of treatment is established by the doctor individually, but not less than 1 month.

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